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Reply to "Donald Trump is Unstoppable."

Republican presidential candidates, Sen. Marco Rubio, R-Fla., left, Donald Trump, Sen. Ted Cruz, R-Texas, and Ohio Gov. John Kasich, right, stand together before the start of the Republican presidential debate sponsored by CNN, Salem Media Group and the Washington Times at the University of Miami, Thursday, March 10, 2016, in Coral Gables, Fla. [AP Photo/Alan Diaz)

Columbus, Ohio (CNN) For Republicans dead set on stopping Donald Trump, Tuesday represents a final chance to seriously impede his path to the party's presidential nomination.

On the Democratic side, it'll be yet another test of Hillary Clinton's organizational strength and backing among party loyalists against Bernie Sanders' ability to expand the electorate and win in diverse states.

Five states hold their Republican and Democratic primaries on Tuesday: Florida, Illinois, Missouri, North Carolina and Ohio.

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