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quote:
Originally posted by Rosita:
Shanaz, Cancer does not discriminate. Sadly, it's becoming almost viral as studies have shown that 1 in 8 Canadians could be hit with Cancer. May she RIP.


This brings me back to Zahra, Sabrina's friend who passed away due to cancer recently. One in eight Canadians is a high rate for getting cancer. Did the study show the reason for it?
FM
Cancer patients have been left free of the disease after being treated with a new drug which harnesses the power of their own immune cells.

Cancer and immunotherapy Q and A
Immunotherapy: could it be the cure for cancer?
Cancer patient recovers after injection of immune cells

Four of 38 patients with non-Hodgkin's lymphoma have seen "complete regressions" following treatment, while five others saw reductions of 50 per cent in their tumours.


The drug, which could prove cheaper than other therapies that try to achieve the same effect with cells, works by activating the body's own defences to attack the cancer.


The results have been described as an "exciting" and "significant" development in the use of immunotherapy, the process of using the body's own immune system to fight disease.


While the trials were only carried out on patients with the blood cancer, it is hoped the methods can be adapated to tackle other cancers.


The disease claims the lives of more than 150,000 people in the UK every year and more than one million people are suffering from cancer at any one time.

Earlier this year doctors announced that a patient with advanced skin cancer was free of the disease two years after they injected him with billions of his own immune cells using a different method. However, experts warned at the time that the process could prove extremely expensive.

The development of the drug could prove a much cheaper alternative way of providing immunotherapy treatments.

Professor Peter Johnson, Cancer Research UK's chief clinician, said: "These exciting preliminary results come from using them to harness the body's own immune response in a new way. Although the side effects need to be monitored carefully, we hope that this type of treatment will prove to be active in larger trials in the future"

"This a significant study," said Dr Cassian Yee, Fred Hutchinson Cancer Research Center, Seattle, who has had significant results using the alternative method of treating patients with white blood cells grown in the lab.

"It remains to be seen if most of the responses are longlasting. Certainly the results are very promising."

The drug, which has been developed by Micromet, in Bethesda, Maryland, was trialled by a team led by Dr Ralf Bargou at University of WÞrzburg in WÞrzburg, German.

The results, published in the journal Science, are encouraging because they suggest that the bigger the dose, the bigger the effect.

Coauthor of the study Dr Patrick Baeuerle, of Micromet, said all seven who received the highest dose responded to the drug.

"Two of the seven had a complete response, and five a partial regression (greater than 50 per cent reduction of tumour).".

The longest duration of a response was so far seen in a patient who received one quarter of their dose. After 13 months, he remains free of the blood cancer.

There are adverse side effects involved, however, such as fevers and chills, occasionally with confusion and tremor, though all stopped after treatment ceased.

Now a further trial is investigating how the drugs works in patients with another form of blood cancer, called acute lymphoblastic leukaemia.

Trials with a similar drug are also under way on patients with another type of cancer, which affects glandular tissue and can appear in the lungs, prostate, breast, colon and elsewhere in the body.

Micromet targets the body's own white blood cells on the cancer, using a fraction of a millionth of a gram of a specialised protein called a "bispecific antibody".

The company has created antibodies, called BiTE antibodies, which are able to stick to sites with exquisite precision, in this case to activate specialised white blood cells ( T cells) to attack cancer.

The antibodies overcome a key problem with immunotherapy that as tumours become more advanced they become more "invisible" to the T cells because the cancer cells lack molecules for white blood cells to hang on to and stage their attack.

Normal antibodies are designed to latch on to one molecular target but the bispecific antibody developed by Micromet, given the name blinatumomab, binds to two, the cancer cell and the T cell, and bring the two together to target the immune system on the cancer.

The team tried varying doses of blinatumomab in patients, and found that among 38 patients, at doses from 0.0005 to 0.06 milligrams (millionths of a gram) per square metre of body surface per day, 11 of them exhibited major responses and tumour shrinking. The disease was cleared from bone marrow, spleen and liver too.

http://www.telegraph.co.uk/sci...boost-treatment.html
Sunil
quote:
Originally posted by Rosita:
Actually the study said 1 in 8 gets breast cancer. It's on the Cancer Society Website. Not sure what they are basing the research on.

I think Sunil is right, we moved into a new development 6 years ago and a lot of health issuse have arisen and one person even said that they think the soil is toxic.


You should have a radon gas test done in your basement.
Sunil
People have been living in Canada for Centuries, why the problem now??
quote:
Originally posted by Cobra:
Rosita, you need to relocate to the USA and pass the message onto others. That is sad news indeed. If child-bearing parents get the disease, they may pass it on to their children, and it's going to be a generation likely to get cancer.
Nehru
A woman claims she is lucky to be alive - after her husband realised she had breast cancer when she developed a bizarre addiction to lettuce.

Elsie Campbell, 59, suddenly couldn't get enough of the leafy vegetable but had no idea why.

But husband Jim, a forensic scientist, believed the new habit could be her body's way of signalling she was ill.
Jim Campbell realised his wife's sudden love of lettuce could be her body's way of signalling she was suffering from a more serious health problem
He realised that a lack of sulforaphane, found in lettuce, can often be a sign of breast cancer - and encouraged his worried wife to visit her GP just in case.

The couple, from Derby were horrified when tests came back positive - and Elsie was diagnosed with cancer.

But thanks to her early diagnosis, she was able to make a full recovery - and credits him with saving her life.

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Elsie, an accounts assistant, said: 'I'd always eaten it in salads, but suddenly, I just couldn't get enough of it.

'I could eat three or four whole lettuces a day.

'I'd eat a whole iceberg lettuce at work, and sit on the bus on the way home thinking about eating more and more.

'I knew something wasn't quite right - and my husband and my sons started to get quite worried about me.

Elsie Campbell, 59, developed a sudden inexplicable craving for lettuce. Her husband realised she could be deficient in sulforaphane
'Jim started investigating which nutrients and minerals were found in lettuce - and realised they were the same ones that your body can be deprived of when it is fighting cancer.

'Not long afterwards, I discovered a small dimple on my breast - and my doctor confirmed I had breast cancer.'

Jim, who has written a book on nutrient deficiencies and what they mean, said: 'As a scientist, I know that everything has to have a cause and effect.

'Elsie didn't start eating lettuce for no reason, so I started to do some research into which minerals and vitamins are found in it.

'I discovered lettuce, like a lot of green veg, contains sulforaphane - which can attack cancer cells.
'I wondered if that was the reason why her body was craving it, and suggested that Lucinda visited the doctor.
'Coincidentally, she discovered the small dimple on her breast the same day.

'Her lettuce cravings really were a warning sign - if she hadn't suspected something was wrong, she would have probably never found the dimple, or certainly would not have been so concerned about it.'

Elsie had the small lump removed from her breast - and underwent months of gruelling treatment, but has now been given the all clear.

She added: 'Strangely, as soon as the lump was removed, I haven't wanted to eat a single lettuce leaf; the cravings completely vanished.'

http://www.dailymail.co.uk/hea...TTUCE-addiction.html
Sunil
I am going to get a radon kit and do the testing in the basement however i will have to find a way of getting the soil tested.'

Nehru, centuries ago people weren't so exposed to all sorts of chemical that we are today. Unfortunately the more civilized we become, the more harm we do to ourselves. Even when we think we are eating organics, there is no guarantee.
FM

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